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Note
The proceedings for Affinity 2011 will be published in the Journal of Molecular Recognition. Please contact Gidi Fleminger (gidifl@post.tau.ac.il) if you are interested in publishing your work.
Thursday June 16, 2011
Opening
The history of ISMR
K. Mosbach, University of Lund/S
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Evolutionary Engineering for Affinity and Drug Design
C. Lowe, University of Cambridge/UK
C. Roque, Universidade Nova de Lisboa, Caparica/P
Keynote
Computational modeling and combinatorial techniques for the design and implementation of novel affinity adsorbents for biopharmaceuticals
C. Lowe, University of Cambridge/UK
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Learning from nature to improve biomimetic affinity ligands for antibody purification
R.J.F. Branco, A.M.G.C. Dias, A.C.A. Roque, Universidade Nova de Lisboa, Caparica/P
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Engineering bispecificity into a single albumin-binding domain aimed for drug targeting and in vivo half-life extension
J. Nilvebrant, T. Alm, S. Hober, J. Löfblom, Royal Institute of Technology, Stockholm/S
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Protein-Protein interactions via stabilization energy between side chains of amino acids at the interaction interface
J. Vondrasek, J. Kysilka, B. Fackovec, Academy of Sciences of the Czech republic, Prague/CZ
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Identification of Ceramic Fluorapatite-binding Peptides from Phage Display and Synthetic Combinatorial Library: Application in Affinity Based Bioseparation
T. Islam, J. Futuwi, R.R. Vennapusa, M. Fernández-Lahore, Jacobs University, Bremen/D
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Kinetics and Thermodynamics of Biomolecular Interactions
H. Jennissen, University of Duisburg-Essen/D
J. Asenjo, University of Chile, Santiago/RCH
Pierce Award and Keynote
Staphylococcal protein A and camelid antibody affinity chromatography: engineering principles and surface characterization
A. Jungbauer, University of Natural Resources and Life Sciences, Vienna/A
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Intelligent interaction analysis using microscale thermophoresis
M. Jerabek-Willemsen, C.J. Wienken, Center for NanoScience (CeNS) and University of Munich/D; S. Duhr, P. Baaske, NanoTemper GmbH, Munich/D
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Comprehensive study of the interactions between nucleotides and chromatography supports provided by STD-NMR spectroscopy
C. Cruz, Universidade da Beira Interior, Covilhã/P; E.J. Cabrita, University Nova Lisboa, Lisboa/P; R.E.F. Boto, P. Almeida, J.A. Queiroz, Universidade da Beira Interior, Covilhã/P
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Antibodies, ion-exchangers, and aptamers: three modes of protein recognition
K. Kourentzi, I. Kanakaraj, J. Fu, W. Chen, University of Houston, TX/USA; N. Taylor, Rice, University, Houston, TX/USA; A. Potty, U. Strych, University of Houston, TX/USA; C. Landes, Rice University, Houston, TX/USA; R.C. Willson, University of Houston, TX/USA
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Isoforms of the monoclonal anti-Rh(D) exert different antigen-binding properties through N-terminal modification
A. Tscheliessnig, University of Natural Resources and Life Sciences, Vienna/A; R. Tscheliessnig, Austrian Centre of Industrial Biotechnology, Vienna/A; T. Teo, N. Wong, Y. Y. Lee, J. Chusainow, R. Philp, M. M. Lee, Bioprocessing Technology Institute, Singapore/SGP; J. Grzeskowiak, University of Natural Resources and Life Sciences, Vienna/A; A. Choo, Bioprocessing Technology Institute, Singapore/SGP; A. Jungbauer, University of Natural Resources and Life Sciences, Vienna/A
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Transient-state kinetics of protein adsorption on solid surfaces measured by the ''boundary-layer exchange by bubble'' (BLEB) method
H.P. Jennissen, M. Meißner, T. Zumbrink, University of Duisburg-Essen, Essen/D
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Prostate specific antigen: serine protease activity and Zinc inhibition - kinetic and structural aspects
N. Mrabet, Nancy University School of Medicine/F; K. Chadha, Roswell Park Cancer Institute, New York/USA; A.K Satheesh Babu, M.A Vijayalakshmi, Centre for Bioseparation Technology, Vellore/IND
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Studies of membrane protein interactions: challenges, possibilities and success stories
S. Löfås, R. Karlsson, GE Healthcare Bio-Sciences AB, Uppsala/S
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Friday June 17, 2011
Affinity Interactions in Cell Biology & Health
J. Gonçalves, Universidade de Lisboa/P
A. Plückthun, University of Zurich/CH
Keynote
Towards single-molecule proteomics with designed binding proteins
A. Plückthun, University of Zurich/CH
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Natural and small molecule-driven exchange of MHC class II bound peptides for the modulation of immune reponses
S. Guenther, FMP/MDC, Berlin/D; A. Schlundt, J. Sticht, FMP/FU, Berlin/D; Y. Roske, U. Heinemann, MDC, Berlin/D; K.H. Wiesmueller, G. Jung, EMC, Tuebingen/D; K. Falk, MDC, Berlin/D; O. Roetzschke, SigN, Singapore/SGP; C. Freund, FMP/FU, Berlin/D
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Epitope mapping of HPA antibodies
B. Hjelm, C. Fernandez, B. Forsström, Royal Institute of Technology, Stockholm/S; H. Johannesson, Atlas Antibodies AB, Stockholm/S; J. Löfblom, J. Rockberg, S. Ståhl, M. Uhlén, Royal Institute of Technology, Stockholm/S
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Targeting viral infectivity factor (Vif) as a molecular therapy approach against HIV-1
S.S. Soares, L. Pedro, G.N.M. Ferreira, Universidade do Algarve, Faro/P
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A method for directed conjugation of affinity molecules
A. Konrad, A. Eriksson Karlström, S. Hober, Royal Institute of Technology, Stockholm/S
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Transient biological interactions and their applications in diagnostics and drug discovery
S. Ohlson, Linnaeus University, Kalmar/S
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Real time interaction analysis of 125I-EGF - EGFR on living cells reveals intriguing complexity and cell context dependency
H. Björkelund, L. Gedda, K. Andersson, Uppsala University/S
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Biomaterials, Biomimetics & Self Assembling
K. Haupt, Université de Technologie de Compiègne/F
K. Mosbach, University of Lund/S
Keynote
Molecularly imprinted nanogels as specific enzyme inhibitors
K. Haupt, Université de Technologie de Compiègne/F
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Studies on molecular recognition ability of computationally designed gallic acid based molecularly imprinted polymers
S. Pardeshi, Visvesvaraya National Institute Of Technology, Nagpur/IND; R.S. Dhodapkar, National Environmental Engineering Research Institute, Nagpur/IND; A. Kumar, Visvesvaraya National Institute Of Technology, Nagpur/IND
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Bone grafting materials as affinity taylored biomaterials for the immobilisation of rhBMP-2
M. Laub, University of Duisburg-Essen, Essen/D; K. Zurlinden, Morphoplant GmbH, Bochum/D; H.P. Jennissen, University of Duisburg-Essen, Essen/D
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Molecularly imprinted polymer films as sensory materials for the selective detection of carboxylates via fluorescence enhancement
M. Biyikal, W. Wan, BAM Federal Institute for Materials Research and Testing, Berlin/D; R. Wagner, B. Sellergren, Dortmund University of Technology/D; K. Rurack, BAM Federal Institute for Materials Research and Testing, Berlin/D
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The titanium dioxide-binding protein - DLDH: structure and function as a modulator of cellular adhesion to titanium dioxide surfaces
G. Fleminger, Tel Aviv University/IL
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Saturday June 18, 2011
Affinity Based Bioprocessing - Glyco-Compounds in Bioprocessing
M.A. Vijayalakshmi, Université de Technologie de Compiègne/F
Terminal-specific PEGylation of rhEGF using self-cleavable intein affinity tag
J.H. Kang, Hanyang University, Ansan/ROK; E.K. Lee, Kyungwon University, Seongnam/ROK
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Affinity and selectivity in the separation of glyco-compounds
H. Rosenfeld, B. Niemeyer, Helmut-Schmidt University, University of the Federal Armed Forces, Hamburg/D
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Glycolipids: improvement of therapeutic potential through the design of novel recovery processes
A. Ribeiro, H. Azevedo, F. Castro, H. Ribeiro, University of Lisbon/P
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Affinity based purification of human monoclonal antibodies from CHO cell supernatants using boronic acid magnetic particles
L. Borlido, A.M. Azevedo, Institute for Biotechnology and Bioengineering, Lisboa/P; A.C.A. Roque, 3 REQUIMTE/CQFB, Caparica/P; M.R. Aires-Barros, Institute for Biotechnology and Bioengineering, Lisboa/P
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One step preparative protein purification using affinity based magnetic microsorbents and automated high gradient magnetic filtration
P. Miethe, A. Preußer-Kunze, K. Frankenfeld, fzmb GmbH Research Centre for Medical Technology and Biotechnology, Bad Langensalza/D; C. Müller, M. Franzreb, Karlsruhe Institute of Technology/D
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Affinity Based Bioprocessing - Nucleic Acids Bioprocessing
R. Aires-Barros, Instituto Superior Técnico, Lisbon/P
J. Quiroz, Universidade da Beira Interior/Portugal
Keynote
Molecular tools - optimization and use of affinity molecules
S. Hober, Royal Institute of Technology, Stockholm/S
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On the adsorption of cell impurities from plasmid-containing lysates to phenyl boronate beads
A.G. Gomes, A.M. Azevedo, M.R. Aires-Barros, D.M.F. Prazeres, Insituto Superior Técnico, Lisbon/P
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Amino acids as ligands for the affinity purification of plasmids in aqueous two-phase systems
P.A. Jorge, N.M. Silva, J.A. Martins, J.C. Marcos, University of Minho, Braga/P
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A new effective method for purifying Escherichia coli small and ribosomal RNA using histidine affinity chromatography
A. Martins, J.A. Queiroz, F. Sousa, University of Beira Interior, Covilhã/P
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Affinity Based Bioprocessing - Noval Supports & Models for Chromatography
G. Ferreira, University of Algarve, Faro/P
A. Jungbauer, University of Natural Resources and Life Sciences, Vienna/A
Adsorption of proteins and peptides with polymer controlled permeation to affinity binding sites of immobilized metal ions
O. Gonzalez-Ortega, J. Porath, R. Guzman, The University of Arizona, Tucson, AZ/USA
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A mathematical model for protein purification with affinity membranes
C. Boi, Università di Bologna/I; S. Dimartino, University of Canterbury, Christchurch/NZ; G.C. Sarti, Università di Bologna/I
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The role of affinity in the rational selection and mathematical modelling of the chromatographic purification of proteins
J. Asenjo, G. Sandoval, University of Chile, Santiago/RCH; C. Shene, University of La Frontera, Temuco/RCH; B.A. Andrews, University of Chile, Santiago/RCH
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YIA - Young Investigator Award
Selected poster presentations
and Journal of Molecular Recognition YEAR Travel Bursaries for Young Scientists
S. Hober, Royal Institute of Technology, Stockholm/S
A. Azevedo, Instituto Superior Técnico, Lisbon/P
Development of a Protein G mimetic for the purification of immunoglobulins based on the Ugi reaction
G. El Khoury, L.A. Rowe, C.R. Lowe, University of Cambridge/UK
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Nanofitins as a source of stable proteins with affinity and specificity
for a given target: example of anti-human IgGs as an alternative to Protein A
G. Béhar, S. Colinet, Université de Nantes/F; M. Bellinzoni, CNRS URA 2185, Paris/F; M. Maillasson, L. Paillard, Université de Nantes/F; D. Tello-Manigne, P.M. Alzari, CNRS URA 2185, Paris/F; X. He, Bio-Rad Laboratories, Hercules/USA; B. Mouratou, F. Pecorari, Université de Nantes/F
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High throughput purification of monoclonal antibodies - evaluation of a new generation of protein A resins
E. Müller, TOSOH BIOSCIENCE GmbH, Stuttgart/D; U. Breuninger, University of Applied Science, Esslingen/D
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Sunday June 19, 2011
Nanotec & Single Molecule Detection
R. Wilson, University of Texas, Houston, TX/USA
G. Ferreira, University of Algarve, Faro/P
Keynote
Affinity at the micro and nano scales: diagnostic applications
R. Wilson, University of Texas, Houston, TX/USA
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Mechanical properties of biological films with the QCM
B. Tomé, J. de-Carvalho, R.M. Rodrigues, G.N.M. Ferreira, University of Algarve, Faro/P
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Highly sensitive microfluidic pathogen detector system based on micro-retroreflector immunoassays
J. Knoop, E. Cacao, T. Sherlock, B. Raja, A. Kar, K. Kourentzi, S. Kemper, P. Ruchhoeft, University of Houston, TX/USA; J. Olano, University of Texas Medical Branch at Galveston, TX/USA; R. Atmar, Baylor College of Medicine, TX/USA; R. Renzi, A. Hatch, Sandia National Laboratory, Livermore, CA/USA; R. Willson, University of Houston, TX/USA
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Amorphous silicon photodiode as a platform for biomolecular interaction detection
C. Vistas, Institute for Biotechnology and Bioengineering, Faro/P; J.P. Conde, INESC Microsystems and Nanotechnologies, Lisbon/P; G.N.M. Ferreira, Institute for Biotechnology and Bioengineering, Faro/P
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Microtiter plates as a representative system for enzymatic hydrolysis with PVA-lens shaped particles
M.A. Nunes, University of Lisbon/P; P.C. Fernandes, Instituto Superior Técnico, Lisboa/P; M.H. Ribeiro, University of Lisbon/P
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Testing G protein coupled receptor targets in cells at different scales using fluorescence microscopy: a tool for the development of microfluidic platforms
J. Trabuco, S.A.M. Martins, G.A. Monteiro, IST, Lisboa/P; V. Chu, J.P. Conde, INESC Microsistemas e Nanotecnologias, Lisboa/P; D.M.F. Prazeres, IST, Lisboa/P
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Real-time single-molecule imaging of HIV-1 capture by mature dendritic cells
O. Esteban, Institute for Bioengineering of Catalonia (IBEC), CIBER-BBN, Barcelona/E; N. Izquierdo-Useros, J. Martínez-Picado, IrsiCaixa Foundation, Badalona/E; M.F. García-Parajo, Institute for Bioengineering of Catalonia (IBEC), CIBER-BBN, Barcelona/E
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